Rhone-Alpes Bioinformatics Center


The recent sequencing of the genome of the pea aphid (Acyrthosiphon pisum), together with the already available sequence of its primary symbiont (Buchnera aphidicola) genome, prompted us - during the genome annotation phase - to develop AcypiCyc : a BioCyc database dedicated to the pea aphid. This metabolic reconstruction was driven by the development of CycADS (Cyc Annotation Database System) : an automated annotation management system that allows the seamless integration of the latest sequence information into metabolic networks reconstruction.

CycADS publication in the journal "Database" A paper describing the CycADS database and the development of AcypiCyc has been published in the journal "Database" (Oxford Journals).

Vellozo AF, Véron AS, Baa-Puyoulet P, Huerta-Cepas J, Cottret L, Febvay G, Calevro F, Rahbé Y, Douglas AE, Gabaldón T, Sagot MF, Charles H and Colella S. CycADS : an annotation database system to ease the development and update of BioCyc databases.

Database, doi : 10.1093/database/bar008, 2011. [Database - Open Access]

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